Zika IgG/IgM rapid Test for specific zika antibody in serum/plasma or whole blood Assay+
Intended use : One step zika virus IgG/IgM test is for in vitro diagnostic use only. This test is an immunochromatographic assay for fast and easy test to detect zika antibody.
Introduction
Zika virus is a member of genus flavivirus, transmitted by Aedes mosquitoes, the same Aedes mosquitoes are also the carrier and the transmitter of dengue virus. Aedes mosquitoes distribute in tropical and subtropical regions throughout the world. The clinical symptoms of zika infection includes fever, conjunctivitis, transient arthritis / arthralgia and maculopapular rash, usually starting from face to spread out the body. Currently no specific treatment is available for zika infection. Except the symptoms described above, zika infection can cause microcephaly, even fatality for new born baby and GuillainBarr syndrome for adult.
one step zika rapid test can detect over 80% zika IgG and IgM in sensitivity and over 96% for specifity without the cross-reaction with dengue.
Assay principle
The recombinant zika antigens are used for each test individually, serum/plasma or whole blood from zika infection is loaded to zika test device, the specific Zika antibodies in specimen will bind to gold-conjugated zika antigen forming zika antibody colloid gold - zika antigen complex. While the complex migrating along nitrocellulose membrane, the complex is captured by the test lines coated with anti-human IgG or IgM causing a pink to deep pink band at the IgG or IgM test line.
