Name:Hydroxypropyl-Gamma-Cyclodextrin;Hydroxypropyl-γ-Cyclodextrin;
Abbreviation:HP-γ-CD
CAS NO. :128446-34-4
MF : C48H80-nO40.(C3H7O)n
​MW: 1297.2+n.(58.1)
Certification: ISO9001, USP-NF, GMP Â
Hydroxypropyl gamma cyclodextrin solubilizes large molecules, such as cholesterol, for use in cell cultures. Hydroxypropyl gamma cyclodextrin is similar to beta cyclodextrin but can dissolve larger molecules.
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The water solubility of the hydroxypropyl-γ-cyclodextrin product after hydroxypropylation is further increased to 80g/100ml (25°C). At the same time, the hydroxypropyl-γ-cyclodextrin is no longer a single pure product. Rather, it is a mixture of multiple substitutions that coexist. When included with guest molecules, inclusion complexes are less likely to crystallize and precipitate. Generally speaking, hydroxypropyl-γ-cyclodextrin has higher solubility in water and stronger resistance to crystallization and precipitation. ability. The solubility of γ-cyclodextrin in water is 23.2g/100ml (25℃). In some cases, the solubility still limits its application.
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It is recommended to be used in higher value-added products, such as special materials such as medicines, health products, cosmetics, or larger molecules that cannot be included by hydroxypropyl-β-cyclodextrin.